Surgical intervention during chemotherapy of gestational trophoblastic neoplasms

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patients with metastatic gestational trophoblastic neoplasms and no gynecological symptoms

early recognition of gestational trophoblastic neoplasm (gtn) will maximize the chances of cure with chemotherapy but some patients present with many different symptoms months or even years after the causative pregnancy making diagnosis difficult. clinicians should be aware of the possibility of gtn in any reproductive age woman with bizarre central nervous system, gastrointestinal, pulmonary s...

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Gestational trophoblastic neoplasia.

Trophoblastic neoplasms are a truly fascinating set of diseases that arise from a failed gestation. A molar pregnancy is an allograft of fetal tissue typically containing only paternal chromosomes that may invade the maternal decidua following a failed gestation that may have arisen up to decades earlier. Choriocarcinoma (CCA), the most common malignant form of trophoblastic disease, represente...

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Gestational Trophoblastic Disease

In partial molar pregnancies, the trophoblast cells have three sets of chromosomes (triploid). Two sperm are believed to fertilise the ovum at the same time, leading to one set of maternal and two sets of paternal chromosomes. Around 10% of partial moles are tetraploid or mosaic in nature. There is usually evidence of fetal tissue or fetal blood cells in a partial molar pregnancy. An embryo may...

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Gestational trophoblastic disease.

BACKGROUND Molar pregnancy represents a significant burden of disease on the spectrum of Gestational Trophoblastic Disease (GTD). The incidence appears to be quite high in South Asia. The objective of this study was to determine the frequency of GTD, and clinical presentation, management and outcome of patients with molar pregnancy. METHODS This retrospective, descriptive study was conducted ...

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Gestational trophoblastic disease.

OBJECTIVE To provide standards for the diagnosis and treatment of patients with hydatidiform mole and gestational trophoblastic tumours (GTT). OPTIONS Prognostic factors useful for treatment decisions in GTT are defined with patients classified as low-, medium-, and high-risk groups. OUTCOMES Improved mortality and morbidity. EVIDENCE Evidence was gathered using Medline for relevant studi...

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ژورنال

عنوان ژورنال: Cancer

سال: 1966

ISSN: 0008-543X,1097-0142

DOI: 10.1002/1097-0142(196611)19:11<1517::aid-cncr2820191109>3.0.co;2-d